Dolutegravir (DTG)
Strength: 50 mg
Dosage Form: Tablet
Description:
Dolutegravir is an integrase strand transfer inhibitor (INSTI) that blocks the HIV integrase enzyme, preventing viral DNA from integrating into the host genome and stopping HIV replication.
Key Features:
- Once-daily dosing without food restrictions
- High barrier to resistance development
- Rapid viral load reduction
- Generally well tolerated
Precautions:
- Possible hypersensitivity reactions; seek immediate medical help if rash or fever occurs
- May interact with certain other medications
- Monitor liver enzymes if co-infected with hepatitis